{
  "id": "cond-mat/0601244",
  "version": "v1",
  "published": "2006-01-12T05:24:38.000Z",
  "updated": "2006-01-12T05:24:38.000Z",
  "title": "CSAW: a dynamical model of protein folding",
  "authors": [
    "Kerson Huang"
  ],
  "comment": "16 figures",
  "categories": [
    "cond-mat.stat-mech",
    "cond-mat.soft",
    "physics.bio-ph",
    "q-bio.QM"
  ],
  "abstract": "CSAW (conditioned self-avoiding walk) is a model of protein folding that combines SAW (self-avoiding walk) with Monte-Carlo. It simulates the Brownian motion of a chain molecule in the presence of interactions, both among chain residues, and with the environment. In a first model that includes the hydrophobic effect and hydrogen bonding, a chain of 30 residues folds into a native state with stable secondary and tertiary structures. The process starts with a rapid collapse into an intermediate \"molten globule\", which slowly decays into the native state afer a relatively long quiescent period. The behavior of the radius of gyration mimics experimental data.",
  "revisions": [
    {
      "version": "v1",
      "updated": "2006-01-12T05:24:38.000Z"
    }
  ],
  "analyses": {
    "keywords": [
      "protein folding",
      "dynamical model",
      "gyration mimics experimental data",
      "native state",
      "self-avoiding walk"
    ],
    "note": {
      "typesetting": "TeX",
      "pages": 0,
      "language": "en",
      "license": "arXiv",
      "status": "editable",
      "adsabs": "2006cond.mat..1244H"
    }
  }
}